Viagra 100 mg can stay in the system for up to 20 hours, but it takes about four to five half-lives for a drug to be fully eliminated. How long it is effective differs from person to person. FDA labeling states that 100 mg Viagra is effective for up to four hours, but the effect at four hours is much less than at two hours. The half-life of Pfizer VGR 100 is four hours and is typically considered effective for up to four hours. For a man who’s sexually stimulated and has sex four hours after taking Viagra 100 mg blue pill, evidence suggests that he will still be able to achieve an erection lasting around 14 minutes.
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