If you're looking to start a new business with a budget of $100k, it's important to choose a venture that maximises your investment. Some of the best businesses to start with 100k include franchises, online stores, and software as a service (SaaS) companies. By investing in a proven business model or leveraging the power of technology, you can minimize risk and maximize your chances of success. Be sure to research your options thoroughly and seek guidance from experienced entrepreneurs before making any decisions.